Initial bromocriptine did not change mortality in early, mild Parkinson's disease
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چکیده
منابع مشابه
Initial bromocriptine did not change mortality in early, mild Parkinson disease.
In patients with early, mild Parkinson disease (PD), does the long-term effectiveness of levodopa alone differ from that of levodopa plus selegiline or initial bromocriptine mono-therapy? Randomized {allocation concealed*} †, blinded {data safety and monitoring commit-tee} †,* controlled trial with a mean 9.2-year follow-up. P a t i e n t s 782 patients with a clinical diagnosis of PD. Exclusio...
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Thirty-one patients with Parkinson's disease were treated with the ergot alkaloid bromocriptine, a drug which stimulates dopamine receptors. Bromocriptine had a slight therapeutic effect in patients on no other treatment and an additional effect in patients on levodopa. The mean optimum dosage of bromocriptine, established over a 12 week period, was 26 mg daily. In 20 patients bromocriptine was...
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ژورنال
عنوان ژورنال: Evidence-Based Medicine
سال: 2002
ISSN: 1356-5524
DOI: 10.1136/ebm.7.3.91